Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB DNA gyrase subunit B	N499Y	-	-	Mycobacterium tuberculosis	ofloxacin\|moxifloxacin\|ciprofloxacin\|levofloxacinfluoroquinolones	ResFinder DatabaseReslit	Confirmed
gyrB	N502D	-	single resistance variant	Mycobacterium leprae	fluoroquinolones	Card Database	Established
gyrB DNA gyrase subunit B	N510D	-	resistance	Mycobacterium tuberculosis	quinolonesfluoroquinolones	Reslit	Candidate
gyrB DNA gyrase subunit B	N538D	AAT->GAT	confers resistance to all four fluoroquinolones tested, resistance, confers resistance to quinolones, multiple resistance variants	Mycobacterium tuberculosis	fluoroquinolonesciprofloxacin\|ofloxacin\|levofloxacin\|moxifloxacinciprofloxacin\|levofloxacin\|moxifloxacin\|ofloxacin+6 more	Card DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	N538I	-	-	Mycobacterium tuberculosis	fluoroquinolones	Reslit	Candidate
gyrB DNA gyrase subunit B	N538K	-	confers resistance to moxifloxacin	Mycobacterium tuberculosis	moxifloxacin	Reslit	Candidate
gyrB DNA gyrase B subunit	N538T	AAC -> ACT	multiple resistance variants	Mycobacterium tuberculosis	fluoroquinolonesofloxacin	Card DatabaseReslit	Confirmed
gyrB DNA gyrase subunit B	N573D	-	-	-	levofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	N573S	-	-	-	levofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	N772K	-	-	-	fluoroquinolones	Reslit	Candidate