Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC topoisomerase IV	S81L	T242C	-	Streptococcus pneumoniae	levofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	S81P	-	-	Mycoplasma hyorhinis, Staphylococcus epidermidis, Staphylococcus aureus, Mycoplasma synoviae	fluoroquinoloneslevofloxacin\|gatifloxacin\|moxifloxacin\|tosufloxacinnemonoxacin\|moxifloxacin\|levofloxacin\|ciprofloxacin+3 more	Reslit	Supported
parC DNA topoisomerase IV subunit C	S81Y	TCA->TAC	-	Streptococcus pneumoniae, Mycoplasma bovis	ciprofloxacinciprofloxacin\|enrofloxacin\|norfloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit A	S82F	-	single resistance variant	Streptococcus pneumoniae	ciprofloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
parC topoisomerase IV	S82I	-	-	Enterococcus faecalis, Yersinia enterocolitica, Salmonella enterica, Staphylococcus aureus, Bacillus subtilis, Acinetobacter pittii, Neisseria gonorrhoeae, Enterococcus faecium	moxifloxacin\|ofloxacinenrofloxacinciprofloxacin+1 more	Reslit	Supported
parC Topoisomerase IV subunit C	S82P	-	-	Bacillus anthracis	ciprofloxacin\|moxifloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	S82R	-	-	Enterococcus faecium	ciprofloxacin	Reslit	Candidate
parC	S82Y	-	single resistance variant	Streptococcus pneumoniae	fluoroquinolones	Card Database	Established
parC DNA topoisomerase IV subunit A	S83A	-	-	Ureaplasma spp., Mycoplasma hominis	levofloxacin\|moxifloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	S83C	-	-	Mycoplasma genitalium	moxifloxacinfluoroquinolones	Reslit	Candidate