Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parE DNA topoisomerase IV subunit E	D401G	-	-	Escherichia coli	ciprofloxacin	Reslit	Candidate
parE DNA topoisomerase IV subunit E	D415N	-	-	E. coli	fluoroquinolones	Reslit	Candidate
parE topoisomerase IV subunit E	D419N	-	-	Pseudomonas aeruginosa	levofloxacin	Reslit	Candidate
parE topoisomerase IV subunit B	D420N	-	DNA topoisomerase IV subunit B ParE	Haemophilus influenzae, Salmonella, Proteus mirabilis, Escherichia coli, Salmonella Typhi, Vibrio sp.	fluoroquinolonesciprofloxacinciprofloxacin\|levofloxacin+4 more	Reference Gene CatalogReslit	Confirmed
parE topoisomerase IV subunit E	D422E	G1265A	-	-	quinolones	Reslit	Candidate
parE DNA topoisomerase IV subunit	D426N	-	-	Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis	levofloxacinofloxacin\|sparfloxacin	Reslit	Candidate
parE	D432H	-	DNA topoisomerase IV subunit B ParE	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established
parE topoisomerase IV subunit E	D432N	-	DNA topoisomerase IV subunit B ParE	Staphylococcus aureus	nemonoxacin\|moxifloxacin\|levofloxacin\|ciprofloxacinquinolones	Reference Gene CatalogReslit	Confirmed
parE	D432V	-	DNA topoisomerase IV subunit B ParE	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established
parE	D434H	-	single resistance variant	Staphylococcus aureus	fluoroquinolones	Card Database	Established