Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parE	M437I	-	single resistance variant, DNA topoisomerase IV subunit B ParE	Pseudomonas aeruginosa	fluoroquinolonesquinolones	Card DatabaseReference Gene Catalog	Confirmed
parE Topoisomerase IV subunit A	M438I	-	Target modification, DNA topoisomerase IV subunit B ParE	Salmonella enterica	nalidixic acidnalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
parE topoisomerase IV subunit E	M591I	-	-	Haemophilus haemolyticus	levofloxacin\|tosufloxacin\|moxifloxacin	Reslit	Candidate
parE DNA topoisomerase IV subunit	N209D	A626G	-	-	ofloxacin	Reslit	Candidate
parE DNA topoisomerase IV subunit B	N404S	-	-	Staphylococcus epidermidis	ciprofloxacin\|ofloxacin\|gatifloxacin\|moxifloxacinlevofloxacin\|gatifloxacin\|moxifloxacin\|tosufloxacinfluoroquinolones	Reslit	Supported
parE topoisomerase IV subunit ParE	N466K	-	-	Mycoplasma genitalium	ciprofloxacin\|garenoxacin\|moxifloxacin\|gatifloxacin\|sparfloxacin\|tosufloxacin\|levofloxacin\|fleroxacin\|norfloxacin\|clinafloxacin\|nadifloxacin\|pazufloxacin	Reslit	Candidate
parE	N470S	-	DNA topoisomerase IV subunit B ParE	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established
parE DNA topoisomerase 4 subunit B	N79S	-	-	Brucella melitensis	fluoroquinolones	Reslit	Candidate
parE DNA topoisomerase IV subunit E	P197S	-	-	Mycoplasma synoviae	enrofloxacin	Reslit	Candidate
parE topoisomerase IV subunit	P394R	-	-	Pseudomonas aeruginosa	ciprofloxacin\|garenoxacin	Reslit	Candidate