Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
penA penicillin-binding protein 2	S363D	-	lowered the acylation rate of penicillin G by 7-fold	Neisseria gonorrhoeae	penicillin	Reslit	Candidate
penA β-lactamase	S72F	-	increased resistance	Burkholderia pseudomallei	amoxicillin\|clavulanic acidamoxicillin clavulanic acid	Reslit	Candidate
penA class A beta-lactamase	T147A	-	-	Burkholderia pseudomallei	ceftazidime	Reslit	Candidate
penA penicillin-binding protein 2	T316P	-	confers high-level resistance to expanded-spectrum cephalosporins	Neisseria gonorrhoeae	ceftizoxime\|ceftriaxonecefixime	Reslit	Candidate
penA class A beta-lactamase	T32A	-	-	Burkholderia multivorans	ceftazidime\|ceftazidime avibactam	Reslit	Candidate
penA penicillin-binding protein 2	T483P	-	-	Neisseria gonorrhoeae	ceftiofur\|ceftriaxone	Reslit	Candidate
penA penicillin-binding protein 2	T483S	-	confers high-level resistance to expanded-spectrum cephalosporins, reduced reactivity for β-lactams, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae, Neisseria meningitidis	ceftizoxime\|ceftriaxoneceftriaxone\|cefiximecefixime+7 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA penicillin-binding protein 2	T485I	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate
penA Penicillin-binding protein 2	T534A	-	-	Neisseria gonorrhoeae	cephalosporins	Reslit	Candidate
penA penicillin-binding protein 2	V279A	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate