Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
blaNDM-5 beta-lactamase	P59A	-	-	E. coli	carbapenems	Reslit	Candidate
blaNDM metallobeta-lactamase	A233V	-	increases protein stability	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	D130G	-	increases protein stability	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	D130N	-	increases protein stability	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	D95N	-	increases protein stability	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	M154L	-	enhances Zn(II) binding affinity	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	M154V	-	enhances Zn(II) binding affinity	Escherichia coli	carbapenems\|penicillin\|cephalosporins	Reslit	Candidate
blaOXA-10 class D beta-lactamase	V117L	-	enhances carbapenemase activity	Escherichia coli, Enterobacter cloacae	meropenem\|ertapenem\|doripenem\|temocillin	Reslit	Candidate
blaOXA-193 oxacillinase	-	G-57T	up-regulation of bla OXA and high-level ß-lactam resistance	Campylobacter coli, Campylobacter jejuni	ampicillin	Reslit	Candidate
blaOXA-23 OXA carbapenemase	H121R	-	-	-	carbapenems	Reslit	Candidate